منابع مشابه
Block of Kcnk3 by protons. Evidence that 2-P-domain potassium channel subunits function as homodimers.
KCNK subunits have two pore-forming P domains and four predicted transmembrane segments. To assess the number of subunits in each pore, we studied external proton block of Kcnk3, a subunit prominent in rodent heart and brain. Consistent with a pore-blocking mechanism, inhibition was dependent on voltage, potassium concentration, and a histidine in the first P domain (P1H). Thus, at pH 6.8 with ...
متن کاملTheory of Scattering of Protons by Protons
quantitatively in agreement, as regards 'magnitudes, variation with angle, and variation with voltage, with a simple phase shift of the spherically symmetrical de Broglie wave ("S wave") due to the collision or scattering, corresponding to a new attractive force overpowering the Coulomb repulsion, and give a rather accurate measure of the "potential well" which is therefore permissible as repre...
متن کاملWeak capture of protons by protons
The cross section for the proton weak capture reaction H(p,eνe) H is calculated with wave functions obtained from a number of modern, realistic high-precision interactions. To minimize the uncertainty in the axial two-body current operator, its matrix element has been adjusted to reproduce the measured Gamow-Teller matrix element of tritium β decay in model calculations using trinucleon wave fu...
متن کاملPotentiation of TRPC5 by protons.
Mammalian members of the classical transient receptor potential channel subfamily (TRPC) are Ca(2+)-permeable cation channels involved in receptor-mediated increases in intracellular Ca(2+). TRPC4 and TRPC5 form a group within the TRPC subfamily and are activated in a phospholipase C-dependent manner by an unidentified messenger. Unlike most other Ca(2+)-permeable channels, TRPC4 and -5 are pot...
متن کاملInvestigation of the direct DNA damages irradiated by protons of different energies using geant4-DNA toolkit
Background: The total yields of direct Single-Strand Breaks (SSBs) and Double-Strand Breaks (DSBs) in proton energies varying from 0.1 to 40 MeV were calculated. While other studies in this field have not used protons with energy less than 0.5 MeV, our results show interesting and complicated behavior of these protons. Materials and Methods: The simulation has been done using the Geant4-DNA too...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2001
ISSN: 0021-9258
DOI: 10.1074/jbc.c100184200